| DOI | Trouver le DOI : https://doi.org/10.1091/mbc.E02-08-0546 |
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| Auteur | Rechercher : Enjalbert, Brice1; Rechercher : Nantel, André1; Rechercher : Whiteway, Malcolm1 |
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| Affiliation | - Conseil national de recherches du Canada. Institut de recherche en biotechnologie du CNRC
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| Format | Texte, Article |
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| Résumé | We used transcriptional profiling to investigate the response of the fungal pathogen Candida albicans to temperature and osmotic and oxidative stresses under conditions that permitted >60% survival of the challenged cells. Each stress generated the transient induction of a specific set of genes including classic markers observed in the stress responses of other organisms. We noted that the classical hallmarks of the general stress response observed inSaccharomyces cerevisiae are absent from C. albicans; no C. albicans genes were significantly induced in a common response to the three stresses. This observation is supported by our inability to detect stress cross-protection in C. albicans. Similarly, in C. albicans there is essentially no induction of carbohydrate reserves like glycogen and trehalose in response to a mild stress, unlike the situation in S. cerevisiae. Thus C. albicans lacks the strong general stress response exhibited byS. cerevisiae. |
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| Date de publication | 2003-04-01 |
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| Dans | |
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| Langue | anglais |
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| Numéro NPARC | 12328563 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | b9c360e5-b67d-4ba8-b933-8f95f892c52d |
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| Enregistrement créé | 2009-09-10 |
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| Enregistrement modifié | 2020-04-02 |
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