| Autre titre | Fish & Shellfish Immunology |
|---|
| DOI | Trouver le DOI : https://doi.org/10.1016/j.fsi.2006.06.012 |
|---|
| Auteur | Rechercher : Fast, M. D.1; Rechercher : Johnson, S. C.2; Rechercher : Jones, S. R. M. |
|---|
| Affiliation | - Conseil national de recherches du Canada. Initiative en génomique et en santé du CNRC
- Conseil national de recherches du Canada. Institut des biosciences marines du CNRC
|
|---|
| Format | Texte, Article |
|---|
| Sujet | vaccination; juvenile salmon; inflammatory; gene expression; anadromous species; bacterial diseases; bacterins; elongation; fish diseases; fish physiology; immune response; inflammation; Oncorhynchus gorbuscha; Oncorhynchus keta; Aeromonas salmonicida; liver; kidney; tumor necrosis factor- alpha; tumours; juveniles; interleukin 8; interleukin 1 |
|---|
| Résumé | Laboratory-reared pink and chum salmon juveniles (2 g) received an intraperitoneal injection with a commercial, unadjuvanted Aeromonas salmonicida bacterin or sterile saline. Relative to elongation factor-1A, expression levels of genes encoding the proinflammatory cytokines interleukin-1?-1 (IL-1?), tumour necrosis factor-?-1 (TNF?) and interleukin-8 (IL-8) in pools of kidney and liver were examined 6- and 24-h after injection. Expression of IL-1? was significantly elevated in pink and chum salmon by 6-h, and declined in pink salmon but not in chum salmon by 24-h. Similarly, expression of TNF? was significantly elevated in both species at 6 h and only in chum salmon after 24-h. Expression of IL-8 was significantly elevated in both species at 6- and 24-h after injection. Expression of the three proinflammatory cytokine genes differed between salmon species both in the timing and magnitude of their expression. The significance of these differences with respect to immune function in these fish requires further research. |
|---|
| Date de publication | 2007-04 |
|---|
| Maison d’édition | Elsevier |
|---|
| Conditions d’utilisation | - Copyright © 2007 Elsevier Ltd. All rights reserved
|
|---|
| Note | yes |
|---|
| Langue | anglais |
|---|
| Publications évaluées par des pairs | Oui |
|---|
| Identificateur | NRC-ACRD-55893 |
|---|
| Numéro du CNRC | 1233 |
|---|
| Numéro NPARC | 3538506 |
|---|
| Exporter la notice | Exporter en format RIS |
|---|
| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
|---|
| Identificateur de l’enregistrement | bd741699-4196-4384-95e8-3fd8dac858d5 |
|---|
| Enregistrement créé | 2009-03-01 |
|---|
| Enregistrement modifié | 2020-05-10 |
|---|
