| Téléchargement | - Voir la version finale : Bioinformatics identification of drug gene modules: application to clear cell carcinoma of the ovary (PDF, 938 Kio)
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| DOI | Trouver le DOI : https://doi.org/10.1109/EMBC.2018.8512230 |
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| Auteur | Rechercher : Tchagang, Alain B.1 |
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| Affiliation | - Conseil national de recherches du Canada. Technologies de l'information et des communications
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| Format | Texte, Article |
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| Conférence | 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), July 18-21, 2018, Honolulu, HI, USA |
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| Résumé | Targeted therapy is a treatment that targets the cancer's specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. Identification of therapeutics targets is a very challenging problem in bioinformatics. An integrative and iterative approach for the identification of drug-gene modules (i.e., groups of genes and drugs such that genes in the same module may regulate each other and are targets of some of the drugs in the same module) is developed. Application to clear cell carcinoma of the ovary data reveals several drug-gene modules and a target network that may play important roles in treating this disease. |
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| Date de publication | 2018-10-29 |
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| Maison d’édition | IEEE |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro NPARC | 23004729 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | e9e93e6d-40a5-4851-a7fe-df388c864a69 |
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| Enregistrement créé | 2018-12-13 |
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| Enregistrement modifié | 2020-05-30 |
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