| DOI | Trouver le DOI : https://doi.org/10.1016/0005-2760(74)90201-X |
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| Auteur | Rechercher : Sundaram, G. S.; Rechercher : Mackenzie, S. L.1; Rechercher : Sodhi, H. S. |
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| Affiliation | - Conseil national de recherches du Canada. Laboratoire régional des prairies
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| Format | Texte, Article |
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| Résumé | The human serum high-density lipoprotein sub-class of hydrated density 1.125–1.21 g/ml (HDL₃) has been shown by preparative isoelectric focusing to consist of at least twelve different subpopulations having reproducible isoelectric points, at 25 °C, ranging from 3.8 to 7.4. Some of the components had isoelectric points identical to those observed for the components of human serum high-density lipoprotein sub-class of hydrated density 1.063–1.125 g/ml (HDL₂). The recombined components were indistinguishable from native HDL3 either by analytical ultracentrifugation or by agarose gel electrophoresis.
When the HDL₃ fractions were combined, all the pooled fractions contained protein, cholesterol and phospholipid but in different amounts. The fractions also differed in their sedimentation coefficients and in their ultraviolet and infrared spectra Polyacrylamide gel electrophoresis of the delipidated fractions showed that the proteins were not uniformly distributed. These data suggest that HDL₃ consists of several discrete lipoprotein subspecies some of which may be different from those in HDL₂. |
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| Date de publication | 1974-02 |
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| Maison d’édition | Elsevier |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Identificateur | 000527607490201X
NRCC-13731 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | f11aeac9-6493-4732-a9d3-9f180c41563a |
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| Enregistrement créé | 2023-12-05 |
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| Enregistrement modifié | 2023-12-05 |
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