| DOI | Trouver le DOI : https://doi.org/10.1007/978-3-7091-0870-3_17 |
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| Auteur | Rechercher : MacKenzie, Roger1; Rechercher : Müller-Loennies, Sven |
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| Affiliation | - Conseil national de recherches du Canada. Thérapeutique en santé humaine
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| Format | Texte, Chapitre de livre |
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| Résumé | Over the past two decades surface plasmon resonance (SPR) has emerged as gold standard technology for the analysis of biomolecular interactions. In the monoclonal antibody (mAb) development area SPR is employed from the early screening stages to detailed characterization of binding kinetics and affinities to epitope mapping to final product testing. This label free technology provides high quality kinetic and affinity data and, in some instances, other unique information not obtained by alternative methods such as ELISA. SPR is well-suited to the study of protein-carbohydrate interactions which are often of low affinity and not easily characterized by other methods. |
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| Date de publication | 2011-10-11 |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro NPARC | 21275592 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | f8fc3930-a093-4628-a8b9-5d649471ac64 |
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| Enregistrement créé | 2015-07-14 |
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| Enregistrement modifié | 2020-03-03 |
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