| Download | - View accepted manuscript: Natural-product-like chiral derivatives by solid-phase synthesis (PDF, 766 KiB)
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| DOI | Resolve DOI: https://doi.org/10.1016/S1367-5931(00)00205-2 |
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| Author | Search for: Arya, Prabhat1; Search for: Baek, Myung-Gi1 |
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| Affiliation | - National Research Council of Canada. NRC Steacie Institute for Molecular Sciences
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| Format | Text, Article |
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| Subject | chemical genetics; combinatorial chemistry; genomics; high-throughput; natural product; proteomics; solid-phase synthesis; stereoselective synthesis; total synthesis; Ugi |
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| Abstract | In this genomics and proteomics age, highly functionalized natural products or natural-product-like compounds are likely to play important roles in understanding the functions of emerging biological targets because they serve as small-molecule chemical probes in modulating a target's specific actions (i.e. activation or deactivation). Development of stereoselective reaction-derived methods on solid phase provides a means of obtaining functionalized chiral core structures that may be used for high-throughout syntheses. |
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| Publication date | 2001-06-01 |
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| In | |
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| Language | English |
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| NPARC number | 12328584 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | d40545ab-97e4-4f1a-8865-b62e55953993 |
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| Record created | 2009-09-10 |
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| Record modified | 2020-03-27 |
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