| Téléchargement | - Voir le manuscrit accepté : Natural-product-like chiral derivatives by solid-phase synthesis (PDF, 766 Kio)
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| DOI | Trouver le DOI : https://doi.org/10.1016/S1367-5931(00)00205-2 |
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| Auteur | Rechercher : Arya, Prabhat1; Rechercher : Baek, Myung-Gi1 |
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| Affiliation | - Conseil national de recherches du Canada. Institut Steacie des sciences moléculaires du CNRC
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| Format | Texte, Article |
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| Sujet | chemical genetics; combinatorial chemistry; genomics; high-throughput; natural product; proteomics; solid-phase synthesis; stereoselective synthesis; total synthesis; Ugi |
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| Résumé | In this genomics and proteomics age, highly functionalized natural products or natural-product-like compounds are likely to play important roles in understanding the functions of emerging biological targets because they serve as small-molecule chemical probes in modulating a target's specific actions (i.e. activation or deactivation). Development of stereoselective reaction-derived methods on solid phase provides a means of obtaining functionalized chiral core structures that may be used for high-throughout syntheses. |
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| Date de publication | 2001-06-01 |
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| Dans | |
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| Langue | anglais |
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| Numéro NPARC | 12328584 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | d40545ab-97e4-4f1a-8865-b62e55953993 |
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| Enregistrement créé | 2009-09-10 |
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| Enregistrement modifié | 2020-03-27 |
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