| DOI | Resolve DOI: https://doi.org/10.1007/BF00684601 |
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| Author | Search for: Smialek, M.; Search for: Sikorska, Marianna1; Search for: Bicz, W.; Search for: Mossakowski, M. |
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| Affiliation | - National Research Council of Canada. NRC Institute for Biological Sciences
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| Format | Text, Article |
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| Subject | glycogen; UDP G-G glucosyltransferase; glycogen phosphorylase; cerebral ischemia |
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| Abstract | The activity of UDPglucose-glycogen glucosyltransferase and of glycogen phosphorylase in the brain of rats subjected to experimental ischemia was in vestigated. A transient increase in UDPglucose-glycogen glucosyltransferase activity was noted in the period between the 12th and 48th h after the operation. The enzyme level returned to its initial value after 72 h of ischemia.
Glycogen phosphorylase activity was studied in preparations with and without 5′ AMP added. The enzyme activity increased from the 12th to the 72nd h of the experiment and returned to normal after 120 h in the brain of rats with ligated arteries, and also in the control group subjected to sham operation.
In normal rats and those anaesthetised only, no changes were found in brain glycogen phosphorylase activity. The enhanced UDPglucose-glycogen glucosyltransferase activity may be responsible for the glycogen deposition in rat brain in experimental ischemia. |
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| Publication date | 1971-06-23 |
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| Publisher | Springer |
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| In | |
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| Language | English |
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| Peer reviewed | Yes |
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| NRC number | SMIALEK1971 |
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| NPARC number | 9377374 |
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| Export citation | Export as RIS |
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| Report a correction | Report a correction (opens in a new tab) |
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| Record identifier | f4bbe341-9d29-4db0-b37c-c42bd73764c1 |
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| Record created | 2009-07-10 |
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| Record modified | 2020-03-13 |
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