| DOI | Trouver le DOI : https://doi.org/10.1007/BF00684601 |
|---|
| Auteur | Rechercher : Smialek, M.; Rechercher : Sikorska, Marianna1; Rechercher : Bicz, W.; Rechercher : Mossakowski, M. |
|---|
| Affiliation | - Conseil national de recherches du Canada. Institut des sciences biologiques du CNRC
|
|---|
| Format | Texte, Article |
|---|
| Sujet | glycogen; UDP G-G glucosyltransferase; glycogen phosphorylase; cerebral ischemia |
|---|
| Résumé | The activity of UDPglucose-glycogen glucosyltransferase and of glycogen phosphorylase in the brain of rats subjected to experimental ischemia was in vestigated. A transient increase in UDPglucose-glycogen glucosyltransferase activity was noted in the period between the 12th and 48th h after the operation. The enzyme level returned to its initial value after 72 h of ischemia.
Glycogen phosphorylase activity was studied in preparations with and without 5′ AMP added. The enzyme activity increased from the 12th to the 72nd h of the experiment and returned to normal after 120 h in the brain of rats with ligated arteries, and also in the control group subjected to sham operation.
In normal rats and those anaesthetised only, no changes were found in brain glycogen phosphorylase activity. The enhanced UDPglucose-glycogen glucosyltransferase activity may be responsible for the glycogen deposition in rat brain in experimental ischemia. |
|---|
| Date de publication | 1971-06-23 |
|---|
| Maison d’édition | Springer |
|---|
| Dans | |
|---|
| Langue | anglais |
|---|
| Publications évaluées par des pairs | Oui |
|---|
| Numéro du CNRC | SMIALEK1971 |
|---|
| Numéro NPARC | 9377374 |
|---|
| Exporter la notice | Exporter en format RIS |
|---|
| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
|---|
| Identificateur de l’enregistrement | f4bbe341-9d29-4db0-b37c-c42bd73764c1 |
|---|
| Enregistrement créé | 2009-07-10 |
|---|
| Enregistrement modifié | 2020-03-13 |
|---|
