Author | Search for: Tunwell, R. E.; Search for: Conlan, J. W.; Search for: Matthews, I.; Search for: East, J. M.; Search for: Lee, A. G. |
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Format | Text, Article |
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Abstract | Epitopes for monoclonal antibodies binding to the native (Ca(2+)-Mg2+)-ATPase have been defined by studying binding to sets of hexameric peptides synthesized on plastic pegs. Epitopes have been confirmed by demonstrating the binding of anti-peptide antibodies to the ATPase. A method is presented for definition of surface-exposed epitopes using polyclonal antibodies. Three surface-exposed epitopes have been defined in the nucleotide-binding domain of the ATPase, suggesting considerable surface exposure of this region. Other surface-exposed epitopes have been located in the region of the fourth stalk domain. |
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Publication date | 1991 |
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Publisher | Portland Press |
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In | |
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Language | English |
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Peer reviewed | Yes |
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NRC number | TUNWELL1991 |
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NPARC number | 9377252 |
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Export citation | Export as RIS |
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Report a correction | Report a correction (opens in a new tab) |
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Record identifier | fc6d729a-862b-4b26-a815-76dab20413b0 |
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Record created | 2009-07-10 |
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Record modified | 2020-03-17 |
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