Auteur | Rechercher : Tunwell, R. E.; Rechercher : Conlan, J. W.; Rechercher : Matthews, I.; Rechercher : East, J. M.; Rechercher : Lee, A. G. |
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Format | Texte, Article |
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Résumé | Epitopes for monoclonal antibodies binding to the native (Ca(2+)-Mg2+)-ATPase have been defined by studying binding to sets of hexameric peptides synthesized on plastic pegs. Epitopes have been confirmed by demonstrating the binding of anti-peptide antibodies to the ATPase. A method is presented for definition of surface-exposed epitopes using polyclonal antibodies. Three surface-exposed epitopes have been defined in the nucleotide-binding domain of the ATPase, suggesting considerable surface exposure of this region. Other surface-exposed epitopes have been located in the region of the fourth stalk domain. |
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Date de publication | 1991 |
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Maison d’édition | Portland Press |
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Dans | |
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Langue | anglais |
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Publications évaluées par des pairs | Oui |
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Numéro du CNRC | TUNWELL1991 |
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Numéro NPARC | 9377252 |
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Exporter la notice | Exporter en format RIS |
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Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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Identificateur de l’enregistrement | fc6d729a-862b-4b26-a815-76dab20413b0 |
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Enregistrement créé | 2009-07-10 |
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Enregistrement modifié | 2020-03-17 |
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