| Téléchargement | - Voir le manuscrit accepté : Enhanced surface plasmon resonance imaging detection of DNA hybridization on periodic gold nanoposts (PDF, 700 Kio)
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| DOI | Trouver le DOI : https://doi.org/10.1364/OL.32.003092 |
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| Auteur | Rechercher : Malic, L.; Rechercher : Cui, B.1; Rechercher : Veres, T.1; Rechercher : Tabrizian, M. |
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| Affiliation | - Conseil national de recherches du Canada. Institut des matériaux industriels du CNRC
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| Format | Texte, Article |
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| Résumé | We explore periodic gold nanoposts as substrates for the enhanced surface plasmon resonance imaging (SPRi) detection of DNA hybridization. Rigorous coupled-wave analysis was used to model and design the nanopost-based SPRi biosensor. Arrayed gold nanoposts on gold-coated glass substrate, with various widths and periodicity, were fabricated using electron-beam lithography and characterized with scanning electron and atomic force microscopy. A scanning-angle SPRi apparatus was used to conduct the kinetic analysis of DNA hybridization on nanopost-based sensor surface and assess the corresponding SPR signal amplification. Experimental results showed that both the nanostructure size and period influenced the SPR signal enhancement; the optimized 30 nm height, 50 nm size, and 110 nm period nanoposts provided a fivefold SPR signal amplification compared with the plain 50 nm thick gold film used as control. |
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| Date de publication | 2007-11-01 |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro du CNRC | NRCC 53678 |
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| Numéro NPARC | 15854994 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | 0b723396-1f7d-49b1-92b3-aa53ac685cec |
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| Enregistrement créé | 2010-07-30 |
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| Enregistrement modifié | 2020-05-10 |
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