Domoic acid: a neurotoxic amino acid produced by the marine diatom Nitzschia pungens in culture

DOI	Trouver le DOI : https://doi.org/10.1139/f88-241
Auteur	Rechercher : Rao, D. V. Subba; Rechercher : Quilliam, M. A.¹; Rechercher : Pocklington, R.
Affiliation du nom	Conseil national de recherches du Canada. Institut des biosciences marines du CNRC
Format	Texte, Article
Résumé	During late 1987, an outbreak of poisoning resulting from the ingestion of cultivated blue mussels (Mytilus edulis) from a localized area in eastern Canada (Cardigan Bay, Prince Edward Island) was assocd. with massive blooms of N. pungens, a widely distributed diatom not previously known to produce toxins; human fatalities resulted. The causative agent, domoic acid, is indeed produced by this diatom. Although no domoic acid could be detected (<2 ng/mL) in culture medium prepd. from Cardigan River water, it was found in cultures of N. pungens grown in this medium at concns. ranging from 0.03 to 0.8 pg/cell in various sep. cultures harvested for chem. anal. 7-68 days after inoculation.
Date de publication	1988-12
Dans	Canadian Journal of Fisheries and Aquatic Sciences 45, nº 12 : 2076–2079.
Langue	anglais
Publications évaluées par des pairs	Oui
Numéro NPARC	23000891
Exporter la notice	Exporter en format RIS
Signaler une correction	Signaler une correction (s'ouvre dans un nouvel onglet)
Identificateur de l’enregistrement	188ee512-748a-4cd2-8547-d6eeb2f08274
Enregistrement créé	2016-11-07
Enregistrement modifié	2020-03-17