Diversity-based organic synthesis in the era of genomics and proteomics

DOI	Trouver le DOI : https://doi.org/10.1002/1521-3773(20010119)40:2<339::AID-ANIE339>3.0.CO;2-J
Auteur	Rechercher : Arya, Prabhat¹; Rechercher : Chou, Doug T. H.¹; Rechercher : Baek, Myung-Gi¹
Affiliation	Conseil national de recherches du Canada. Institut Steacie des sciences moléculaires du CNRC
Format	Texte, Article
Sujet	combinatorial chemistry; heterocycles; molecular diversity; natural products; solid-phase synthesis
Résumé	Is the game over or has it just begun? The technical advances related to genomics and proteomics research have provided the scientific community with large sets of sequence-level genetic information with enormous potential for identification of new drug targets. Gene expression and genome-wide gene sequencing have been successfully accomplished. What is the next step? What will be done with this information? Challenges faced are to identify genes or proteins of interest and to determine the functions of a given gene or protein that we only know at the sequence level at the moment.
Date de publication	2001
Dans	Angewandte Chemie - International Edition 40, nº 2 (2001) : 339–346.
Langue	anglais
Numéro NPARC	12339052
Exporter la notice	Exporter en format RIS
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Identificateur de l’enregistrement	275ff0d3-4b9f-4897-bcca-862f555ec7a4
Enregistrement créé	2009-09-11
Enregistrement modifié	2020-03-27