| Téléchargement | - Voir le manuscrit accepté : QASI, an international quality management dystem for CD4 T-Cell enumeration focused to make a global difference (PDF, 660 Kio)
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| DOI | Trouver le DOI : https://doi.org/10.1002/cyto.b.20487 |
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| Auteur | Rechercher : Bergeron, Michèle; Rechercher : Ding, Tao; Rechercher : Houle, Guy; Rechercher : Arès, Linda; Rechercher : Chabot, Christian; Rechercher : Soucy, Nadia; Rechercher : Seely, Peggy; Rechercher : Sherring, Alice; Rechercher : Bogdanovic, Dragica; Rechercher : Faucher, Sylvie; Rechercher : Somorjai, Ray1; Rechercher : Summers, Randy1; Rechercher : Sandstrom, Paul |
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| Affiliation | - Conseil national de recherches du Canada. Institut du biodiagnostic du CNRC
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| Format | Texte, Article |
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| Sujet | quality management system; quality assessment program; quality assessment schemes; interlaboratory variation; quality awareness; national quality intelligence |
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| Résumé | Background: A significant worldwide mobilization effort to treat people with HIV disease began in 2003. Most guidelines for initiating antiretroviral therapy require reliable and reproducible CD4 T-cell counting. Therefore, any effort that improves global availability of quality managed assessment schemes for CD4 T-cell enumeration is a positive achievement for the clinical management of AIDS on a worldwide scale. Methods: The Canadian QASI-Quality Management System (QMS) has been in operation for over a decade. More recently, QMS has fine-tuned its strategy to optimize its global impact in the fight against the HIV/AIDS pandemic. Three modifications were implemented: (1) introduction of skills and knowledge transfer workshops pertaining to the initiation of national quality management programs for CD4 counting, (2) introduction of a road map to establish domestic EQAP for countries that are ready, and (3) introduction of a statistical analysis package which permits continuous monitoring of global impact of the QASI-QMS. Results: Based on QASI-QMS distribution of specimens over four consecutive participation cycles, there was decreased interlaboratory variation for both low and medium CD4 T-cell levels. After three cycles of consecutive participation, there is an average of 38 and 26% error reduction reported for the mid and low CD4 levels, respectively. Conclusion: The program improvements mentioned earlier appear to have had a profound effect with regard to enhancing the performance of laboratories participating in the QASI-QMS. Specifically, there is a significant reduction in interlaboratory variability of CD4 T-cell counts resulting from continuous participation in the QASI-QMS. © 2009 Clinical Cytometry Society |
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| Date de publication | 2010-01-01 |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro NPARC | 17712967 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | 66b46ced-e5b2-4b85-890f-c3acf0053773 |
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| Enregistrement créé | 2011-04-09 |
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| Enregistrement modifié | 2020-04-17 |
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