| Téléchargement | - Voir la version finale : Quantitative high-throughput analysis of domoic acid in mussel tissue homogenates using laser ablation electrospray ionization – MS/MS (PDF, 532 Kio)
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| Auteur | Rechercher : Beach, Daniel1; Rechercher : Walsh, Callee M.; Rechercher : McCarron, Pearse1 |
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| Affiliation | - Conseil national de recherches du Canada. Science des mesures et étalons
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| Format | Texte, Allocution |
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| Conférence | 30th Montreaux LC/MS Symposium, 3–7 November 2014, Charleston, USA |
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| Résumé | We investigated the use of Laser Ablation Electrospray Ionization (LAESI) with MS/MS detection for Domoic Acid (DA) analysis directly from mussel tissue homogenates without sample extraction, cleanup or chromatographic separation. DA could be selectively detected directly from mussel tissue homogenates using LAESI-MS/MS in selected reaction monitoring scan mode. A matrix matched calibration curve was used to quantify mussel tissue reference materials and results were in good agreement with two established methods, LC-UV and LC-MS/MS, within the linear range. Most notable is the decrease in run time from about 20 minutes for a typical chromatographic method to about 10 seconds per sample for LAESI-MS/MS. |
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| Date de publication | 2014-11 |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro NPARC | 23002022 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | 8a18e683-ac07-4502-a1f5-e6d97c095119 |
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| Enregistrement créé | 2017-07-21 |
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| Enregistrement modifié | 2020-05-30 |
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