| Téléchargement | - Voir le manuscrit accepté : Flow of blood-saline mixtures studied by time-domain optical coherence tomography (PDF, 823 Kio)
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| DOI | Trouver le DOI : https://doi.org/10.1117/12.808041 |
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| Auteur | Rechercher : Popescu, Dan P.1; Rechercher : Sowa, Michael G.1 |
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| Affiliation | - Conseil national de recherches du Canada. Institut du biodiagnostic du CNRC
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| Format | Texte, Article |
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| Conférence | Optical Diagnostics and Sensing IX, 26 January 2009, San Jose, CA, USA |
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| Sujet | time-domain optical coherence tomography; blood; light propagation; attenuation; multiple scattering of light; blood cells; blood-saline flow |
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| Résumé | In-vitro analysis of flowing blood-saline mixtures is performed by time-domain optical coherence tomography imaging. The mixtures contain blood in concentrations ranging from 100% to 20%. For each image, a corresponding compounded profile is obtained by adding one thousand adjacent A-scans. The compounded profiles are used for characterizing the optical coherence tomography signal as it propagates within the studied blood–saline mixtures. The results obtained point toward the possibility of acquiring intra-vascular images of arterial tissue that is located behind slabs of flowing blood-saline. A threshold in the propagation distance beyond which the recorded signal becomes dominated by its multiple scattered components is established along the compounded profiles. The threshold location, at a depth of ~0.6 mm, is independent of blood concentration. Further investigation of the compounded profiles reveals that the region extending to a maximum depth of about 200 μm from the point where the probing beam enters blood-saline mixtures could reveal information about the flow regime. This opens the possibility of another application for time-domain optical coherence tomography in intravascular imaging: assessing the flow regime, i.e. laminar or turbulent. |
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| Date de publication | 2009-03-20 |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Numéro NPARC | 19703847 |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | a163c8ac-764d-4cb3-8b99-be717b020868 |
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| Enregistrement créé | 2012-03-28 |
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| Enregistrement modifié | 2020-04-16 |
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