| Téléchargement | - Voir la version de l’auteur : Interlaboratory comparison on the quantification of total and accessible amine groups on silica nanoparticles with qNMR and optical assays (PDF, 594 Kio)
- Voir les données supplémentaires : Interlaboratory comparison on the quantification of total and accessible amine groups on silica nanoparticles with qNMR and optical assays (PDF, 688 Kio)
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| DOI | Trouver le DOI : https://doi.org/10.1021/acs.analchem.1c02162 |
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| Auteur | Rechercher : Kunc, Filip1; Rechercher : Nirmalananthan-Budau, Nithiya; Rechercher : Rühle, Bastian; Rechercher : Sun, Ying1; Rechercher : Johnston, Linda J.1Identifiant ORCID : https://orcid.org/0000-0002-9136-4920; Rechercher : Resch-Genger, UteIdentifiant ORCID : https://orcid.org/0000-0002-0944-1115 |
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| Affiliation | - Conseil national de recherches du Canada. Centre de recherche en métrologie
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| Format | Texte, Article |
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| Sujet | nanomaterials; amines; nanoparticles; silica; assays |
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| Résumé | Risk assessment of nanomaterials requires not only standardized toxicity studies but also validated methods for nanomaterial surface characterization with known uncertainties. In this context, a first bilateral interlaboratory comparison on surface group quantification of nanomaterials is presented that assesses different reporter-free and labeling methods for the quantification of the total and accessible number of amine functionalities on commercially available silica nanoparticles that are widely used in the life sciences. The overall goal of this comparison is the identification of optimum methods as well as achievable measurement uncertainties and the comparability of the results across laboratories. We also examined the robustness and ease of implementation of the applied analytical methods and discussed method-inherent limitations. In summary, this comparison presents a first step toward the eventually required standardization of methods for surface group quantification. |
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| Date de publication | 2021-10-29 |
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| Maison d’édition | American Chemical Society |
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| Dans | |
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| Langue | anglais |
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| Publications évaluées par des pairs | Oui |
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| Exporter la notice | Exporter en format RIS |
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| Signaler une correction | Signaler une correction (s'ouvre dans un nouvel onglet) |
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| Identificateur de l’enregistrement | f9830435-391e-4ca9-bfe2-5ffc1910998c |
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| Enregistrement créé | 2021-12-03 |
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| Enregistrement modifié | 2021-12-03 |
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