Purification of capsular polysaccharide

Par Conseil national de recherches du Canada

DOI	Trouver le DOI : https://doi.org/10.1385/1-59259-148-5:41
Auteur	Rechercher : Yang, Qingling¹; Rechercher : Jennings, Harold¹
Affiliation	Conseil national de recherches du Canada. Institut des sciences biologiques du CNRC
Format	Texte, Chapitre de livre
Résumé	Meningococcus is an aerobic, fastidious, Gram-negative diplococcus that is found only in humans. Its cell wall has a cytoplasmic membrane, a peptidoglycan layer, and an outer membrane. Meningococci isolated from the bloodstream or the spinal fluid are almost always encapsulated. The capsules are polysaccharides, which consist of repeating sugar units (1,2). The capsular polysaccharide can be isolated, purified, and chemically and physically defined. Based on the chemical and immunological specificity of its capsular polysaccharides, Neisseria meningitidis has been classified serologically into groups A, B, C, 29E, H, I, K, L, W135, X, Y and Z (2). Of these, groups A, B, and C are responsible for approx 90% of meningococcal meningitis, and group B meningococcus is responsible for the majority of meningococcal disease in industrialized countries (1,2). The structures of the repeating units of the meningococcal polysaccharides have been elucidated and are shown in Table 1.
Date de publication	2001
Maison d’édition	Humana Press Springer
Dans	Meningococcal Vaccines (2001) : 41–47.
Série	Methods in Molecular Medicine 66.
Langue	anglais
Publications évaluées par des pairs	Oui
Numéro du CNRC	YANG2001
Numéro NPARC	9366726
Exporter la notice	Exporter en format RIS
Signaler une correction	Signaler une correction (s'ouvre dans un nouvel onglet)
Identificateur de l’enregistrement	fa344fb4-620b-4acc-bf38-46c47218b90e
Enregistrement créé	2009-07-10
Enregistrement modifié	2022-07-07

Date de modification :: 2024-06-29